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National Guide to clinically proven probiotics for use during antibiotic treatment published

At last, clarity on probiotics with a proven effect – Aug. 6, 2018

Today, the National Guide to clinically proven probiotics for use during antibiotic treatment was launched through a publication in the scientific journal BMC Gastroenterology. TNO and ARTIS-Micropia announced their plans to develop the guide on 15 November 2016 during the 'Know Yourself’ Micropia symposium, in the presence of scientists and representatives from professional practice and the business community. The guide contains an overview of clinically proven probiotics that can be used in conjunction with antibiotics to prevent antibiotic-associated diarrhoea (AAD). The guide serves as a tool for patients, consumers and health care practitioners such as GPs, dietitians and pharmacists.

read the publication in BMC Gastroenterology

Positive impact on health

Antibiotics are a frequently used weapon in the fight against bacterial pathogens. However, antibiotic medicines often also affect our the 'good' bacteria that live in our intestines. These gut flora are crucial to optimal intestinal functioning and therefore essential to good health. Antibiotics (especially broad-spectrum antibiotics) can have a disruptive effect on gut flora and trigger a variety of adverse symptoms. This is a common problem, as the broad-spectrum antibiotic amoxicillin – which carries a high risk of such complaints – is the most prescribed antibiotic in the Netherlands, with 1.2 million users in 2017.
One of the most common side effects is AAD. Probiotics are microbes that, if administered in sufficient quantities in dairy drinks or as a dietary supplement, have a positive impact on health. The consumption of certain probiotics during antibiotic treatment has been proven to have a preventive effect and reduce the likelihood of ADD.

Method

Read the story  to learn more about the method of the study conducted by Remco Kort, Micropia professor affiliated with TNO and the Vrije Universiteit Amsterdam and co-authors Ger Rijkers, Cyrille Krul and Valeria Agamennone. The probiotic products were classified according to their proven effect as demonstrated in a minimum of one to three independent clinical studies. Products found to have an effect in at least three of the included studies were awarded three stars, those with effects in two studies were awarded two stars, and those with an effect in one study were awarded only one star. This led to a total of eight single-strain and multi-strain formulae demonstrated to be effective in groups treated with probiotics. The various products are all offered for sale to consumers and can typically be purchased online. The guide will be subject to annual evaluation and updated as necessary.